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HIDEX 300SL TDCR LIQUID SCINTILLATION COUNTER

HIDEX 300SL TDCR LIQUID SCINTILLATION COUNTER

Ingediend door Anoniem (niet gecontroleerd) op vr, 03/10/2023 - 15:33

he most advanced, compact and user friendly LSC on the market

The Hidex 300SL is a revolutionary instrument with compact size, incorporating the most advanced triple-PMT detector technology facilitating:

  • Exceptionally high counting efficiency
  • Luminescence free counting mode
  • Absolute activity counting without external radioactive source using triple-to-double coincidence ratio (TDCR) method.

Optional features include low background detector (PMT) for environmental applications, external Eu-152 standard source for conventional quench correction, and the most advanced and sensitive alpha beta separation with 2D/3D spectrum analysis tool. Alpha beta separation with 2D/3D tool allows reliable and simple assay calibration without laborious misclassification measurements.

Standard model 425-020 is best suited for universities, research institutes and pharmaceutical industry for general nuclear research and biological applications such as cell studies, cytotoxicity measurements and detection of primary C-14 consumption, as well as for swipe tests. Environmental concentrations of alphas e.g. Rn-222 or Ra-226 are possible to measure when equipped with alpha-beta separation option and betas e.g. H-3 and Sr-90 when equipped with low level PMT option.

Compact and transportable

The 300 SL has a modern and compact design measuring half the size and weight of some of its long standing rivals. It is therefore much easier to install and fit it into smaller, more space conscious laboratories, such as transporting in research vessels or mobile labs.

Technical innovations

Absolute activity counting with TDCR technology

The detector with 3 PMTs enable triple-to-double coincidence ratio counting TDCR, which is an absolute counting method for obtaining counting efficiency of the samples without external or internal standard sources. Unlike external standard methods, TDCR is a universal method applicable for both chemical and color quenching, for aqueous and organic samples and for different cocktails and range of isotopes. TDCR method can be used for counting of typical beta isotopes and also for absolute activity determination of Cerenkov radiation e.g. from 90Y/90Sr.

Luminescence free counting

Hidex 300 SL can be used in triple coincidence mode only, which removes interference from chemiluminescence and reduces the effect of other low energy noise events. Samples with long luminescence decay such as 14C in NaOH can be counted immediately without the need to dark adapt.

Exceptionally high counting efficiency

The 300 SL utilizes three PMTs aligned at 120° from each other. Optimum detection geometry yields in better detection geometry than conventional double coincidence detector. And the more there is quenching, the greater the advantage of triple coincidence detector

Example: Efficiency for 3H (in 20 ml vials)
  Hidex 300SL Double Coincidence Counters
Unquenched: > 70 % 65 %
3H in water: > 35 % 25 %
3H in water, high quench: 10% 5 %

 

Alpha/beta separation

Most advanced alpha beta separation is available as an option on the Hidex 300 SL. It facilitates extremely sensitive detection of alpha isotopes in presence of high beta radiation. Calibration and results validation can be done using convenient and reliable 2D/3D spectrum analysis tool without laborious and isotope specific misclassification run. Separation works even for unknown mixture of alpha and beta isotopes. This reduces the possibility on measurement errors typical for conventional misclassification methods, where calibration is done in often in different conditions and isotopes than found in unknown samples. Typical applications include detection of 222Rn, 226/228 Ra, 241 Am and gross alpha/beta.

User friendly software

The 300 SL is operated using an external PC with Windows 7, 8 and 10 based MikroWin 300 SL software, featuring an easy-to-use graphical interface and extensive data reduction capabilities, including quench curve analysis and half-life correction. The software is designed for multiuser environment, enabling unlimited number of methods for different isotopes and easy data export to Excel or other programs. Users can add samples with new methods, and high priority samples while the instrument is counting. MikroWin is also 21 CFR Part 11 compliant.

 

 

Models and technical data

Standard #425-201
  • Sample capacity, 20mL/7mL: 40/96
  • Counting efficiency 3 H/14C (%): 70/96
  • Background 3 H in water (CPM): 12
  • Dimensions, W/H/D (cm): 52/68/63
  • Weight (kg): 125
Super Low Level #425-020
  • Sample capacity, 20mL/7mL: 40/96
  • Counting efficiency 3 H/14C (%): 70/96
  • Background 3 H in water (CPM): 3
  • Dimensions, W/H/D (cm): 52/68/63
  • Weight (kg): 180
Metrology #425-202
  • Sample capacity, 20mL/7mL: 40/96
  • Counting efficiency 3 H/14C (%): 70/96
  • Background 3 H in water (CPM): 12
  • Dimensions, W/H/D (cm): 52/68/63
  • Weight (kg): 125
Optional features

525-003 alpha/beta separation
462-019 External Eu-152 std source
425-2003 Cooling
425-018 LL PM tubes

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